Rocío García-Becerra Selected Research

Astemizole

1/2019	ASTEMIZOLE, AN INHIBITOR OF ETHER-À-GO-GO-1 POTASSIUM CHANNEL, INCREASES THE ACTIVITY OF THE TYROSINE KINASE INHIBITOR GEFITINIB IN BREAST CANCER CELLS.
10/2014	In vivo dual targeting of the oncogenic Ether-à-go-go-1 potassium channel by calcitriol and astemizole results in enhanced antineoplastic effects in breast tumors.
1/2012	Astemizole synergizes calcitriol antiproliferative activity by inhibiting CYP24A1 and upregulating VDR: a novel approach for breast cancer therapy.

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Rocío García-Becerra Research Topics

Disease

28	Neoplasms (Cancer) 12/2021 - 09/2006
21	Breast Neoplasms (Breast Cancer) 12/2021 - 09/2006
5	Carcinogenesis 12/2021 - 02/2010
3	Triple Negative Breast Neoplasms 11/2021 - 01/2019
2	Neoplasm Metastasis (Metastasis) 12/2021 - 05/2011
2	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 01/2020
2	Body Weight (Weight, Body) 10/2017 - 10/2014
2	Uterine Cervical Neoplasms (Cancer of the Cervix) 08/2010 - 07/2010
1	Medulloblastoma 01/2022
1	Hypoxia (Hypoxemia) 12/2021
1	Infections 01/2019
1	Premature Birth (Birth, Premature) 01/2019
1	Carcinoma (Carcinomatosis) 01/2015
1	Glioblastoma (Glioblastoma Multiforme) 05/2013
1	Disease Progression 12/2012
1	Azoospermia 02/2012
1	Hepatocellular Carcinoma (Hepatoma) 01/2012
1	Lymphoma (Lymphomas) 08/2011
1	Fibroadenoma 02/2010
1	Ductal Carcinoma 02/2010
1	Papillomavirus Infections 04/2009

Drug/Important Bio-Agent (IBA)

17	Calcitriol (Calcijex)FDA LinkGeneric 11/2021 - 02/2010
6	Potassium Channels (Potassium Channel)IBA 01/2019 - 04/2009
6	Antineoplastic Agents (Antineoplastics)IBA 11/2016 - 02/2010
5	Biological ProductsIBA 11/2020 - 05/2011
5	Tyrosine Kinase InhibitorsIBA 01/2020 - 01/2015
5	RadiopharmaceuticalsIBA 04/2014 - 06/2009
4	Vitamin D FDA LinkGeneric 01/2021 - 10/2014
4	Hormones (Hormone)IBA 01/2021 - 02/2010
4	Estrogen ReceptorsIBA 01/2021 - 12/2012
4	IntegrinsIBA 11/2019 - 05/2011
4	Calcitriol Receptors (Calcitriol Receptor)IBA 04/2015 - 07/2010
3	EnzymesIBA 01/2021 - 09/2006
3	Estrogen Receptor Modulators (Antiestrogen)IBA 01/2021 - 04/2009
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 02/2010
3	Lapatinib (GW572016)FDA Link 01/2020 - 01/2015
3	Testosterone (Sustanon)FDA Link 01/2019 - 09/2006
3	Gefitinib (Iressa)FDA Link 01/2019 - 01/2015
3	AstemizoleIBA 01/2019 - 01/2012
3	EDDA (NiEDDA)IBA 04/2014 - 06/2009
2	Histone Deacetylases (Histone Deacetylase)IBA 12/2021 - 11/2020
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2021 - 10/2014
2	MicroRNAs (MicroRNA)IBA 12/2021 - 12/2012
2	Pharmaceutical PreparationsIBA 11/2021 - 10/2014
2	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 04/2011
2	Type I Tumor Necrosis Factor ReceptorsIBA 01/2019 - 12/2017
2	CytokinesIBA 01/2019 - 12/2017
2	Vitamin D3 24-HydroxylaseIBA 10/2017 - 01/2012
2	CathelicidinsIBA 10/2017 - 11/2016
2	25-Hydroxyvitamin D3 1-alpha-Hydroxylase (25 Hydroxyvitamin D3 1 alpha Hydroxylase)IBA 10/2017 - 07/2010
2	neratinibIBA 01/2017 - 01/2015
2	Peptides (Polypeptides)IBA 11/2016 - 05/2013
2	Bombesin Receptors (Bombesin Receptor)IBA 04/2011 - 06/2009
2	Ether (Diethyl Ether)IBA 07/2010 - 02/2010
2	Estradiol (Delestrogen)FDA LinkGeneric 01/2009 - 09/2006
1	Protein Kinase CIBA 01/2022
1	Estrogen Receptor betaIBA 01/2022
1	Matrix Metalloproteinases (MMPs)IBA 12/2021
1	pyridineIBA 12/2021
1	Cholecalciferol (Vitamin D3)FDA Link 11/2021
1	AcidsIBA 11/2021
1	cyclo(arginylglycyl)IBA 11/2021
1	4- amino- 5- fluoro- 3- (5- (4- methylpiperazin- 1- yl)- 1H- benzimidazol- 2- yl)quinolin- 2(1H)- oneIBA 11/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2020
1	Caspase 3 (Caspase-3)IBA 01/2020
1	Indomethacin (Indometacin)FDA LinkGeneric 01/2020
1	ResveratrolIBA 11/2019
1	PhytochemicalsIBA 11/2019
1	CurcuminIBA 11/2019
1	Type II Tumor Necrosis Factor ReceptorsIBA 12/2017
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2017
1	Ethanol (Ethyl Alcohol)IBA 10/2017
1	Mixed Function Oxygenases (Monooxygenases)IBA 10/2017
1	Calcifediol (Calcidiol)FDA Link 10/2017
1	seocalcitolIBA 01/2017
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2017
1	SteroidsIBA 05/2016
1	SolutionsIBA 01/2015
1	OzoneIBA 01/2015
1	Oxygen (Dioxygen)IBA 01/2015
1	ErbB Receptors (EGF Receptor)IBA 01/2015
1	Thrombospondin 1IBA 10/2014
1	Tamoxifen FDA LinkGeneric 12/2012
1	Aromatase InhibitorsIBA 12/2012
1	Progesterone CongenersIBA 02/2012
1	CytochromesIBA 01/2012
1	Cytochrome P-450 CYP3AIBA 01/2012
1	Messenger RNA (mRNA)IBA 01/2012
1	PhytohemagglutininsIBA 08/2011
1	GoldIBA 05/2011
1	Estrogen Receptor alphaIBA 08/2010
1	BombesinIBA 06/2009
1	Indicators and Reagents (Reagents)IBA 04/2009
1	Estrogens (Estrogen)FDA Link 04/2009
1	Mifepristone (RU 486)FDA Link 01/2009
1	Protein Isoforms (Isoforms)IBA 01/2009

Therapy/Procedure

13	Therapeutics 12/2021 - 04/2009
3	Drug Therapy (Chemotherapy) 11/2021 - 12/2012
2	Radiotherapy 12/2017 - 04/2011
1	Intraperitoneal Injections 10/2014